Article
Intensified peginterferon α-2a dosing increases sustained virologic response rates in heavy, high viral load hepatitis C genotype 1 patients with high low-density lipoprotein.
Journal of clinical gastroenterology - 1 Mar 2013
Harrison Stephen A, Abdurakhmanov Djamal, Shiffman Mitchell L, Bakulin Igor, Mazur Wlodzimierz, Rodriguez-Torres Maribel, Silva Giovanni Faria, Cheinquer Hugo, Messinger Diethelm, Connell Edward V, McKenna Michael, Tatsch Fernando, Reddy K Rajender
Abstract excerpt
BACKGROUND AND GOAL: Patients infected with hepatitis C virus (HCV) with elevated low-density lipoprotein (LDL) levels achieve higher sustained virologic response (SVR) rates after peginterferon (PegIFN)/ribavirin treatment versus patients with lower LDL. Our aim was to determine whether SVR rates in patients with low/elevated LDL can be improved by dose intensification. STUDY: In PROGRESS, genotype 1 patients...
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