Article
Hypervariable 'minisatellite' regions in human DNA.
Nature - 1 Jan 2000
Jeffreys A J, Wilson V, Thein S L
Abstract excerpt
The human genome contains many dispersed tandem-repetitive 'minisatellite' regions detected via a shared 10-15-base pair 'core' sequence similar to the generalized recombination signal (chi) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci...
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