Hypervariable 'minisatellite' regions in human DNA.

doi:10.1038/314067a0

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Article

Hypervariable 'minisatellite' regions in human DNA.

Nature - 1 Jan 2000

Jeffreys A J, Wilson V, Thein S L

Abstract excerpt

The human genome contains many dispersed tandem-repetitive 'minisatellite' regions detected via a shared 10-15-base pair 'core' sequence similar to the generalized recombination signal (chi) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy nu...

Topics

Alleles
Base Sequence
DNA, Satellite
Genetic Engineering
Genetic Variation
Heterozygote
Humans
Mutation
Nucleic Acid Hybridization
Pedigree
Polymorphism, Genetic
Recombination, Genetic
Repetitive Sequences, Nucleic Acid

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