Article
An RNA aptamer-based microcantilever sensor to detect the inflammatory marker, mouse lipocalin-2.
Analytical chemistry - 16 Oct 2012
Zhai Lijie, Wang Tianjiao, Kang Kyungho, Zhao Yue, Shrotriya Pranav, Nilsen-Hamilton Marit
Abstract excerpt
Lipocalin-2 (Lcn2) is a biomarker for many inflammatory-based diseases, including acute kidney injury, cardiovascular stress, diabetes, and various cancers. Inflammatory transitions occur rapidly in kidney and cardiovascular disease, for which an in-line monitor could be beneficial. Microcantilever devices with aptamers as recognition elements can be effective and rapidly responsive sensors. Here, we have...
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