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Label-Free Electrochemical Biosensor for Monitoring of Chloride Ion in an Animal Model of Alzhemier's Disease.

ACS chemical neuroscience - 15 Feb 2017

Dong Hui, Zhang Limin, Liu Wei, Tian Yang

Abstract excerpt

The potential damage of Alzheimer's disease (AD) in brain function has attracted extensive attention. As the most common anion, Cl- has been indicated to play significant roles in brain diseases, particularly in the pathological process of AD. In this work, a label-free selective and accurate electrochemical biosensor was first developed for real-time monitoring of Cl- levels in a mouse brain model of AD and rat...

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PMID: 27992175
DOI: 10.1021/acschemneuro.6b00296

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