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Article

Influence of ZNF804a on brain structure volumes and symptom severity in individuals with schizophrenia.

Archives of general psychiatry - 1 Sept 2012

Wassink Thomas H, Epping Eric A, Rudd Danielle, Axelsen Michael, Ziebell Stephen, Fleming Frank W, Monson Eric, Ho Beng Choon, Andreasen Nancy C

Abstract excerpt

CONTEXT The single-nucleotide polymorphism rs1344706 in the gene ZNF804a has been associated with schizophrenia and with quantitative phenotypic features, including brain structure volume and the core symptoms of schizophrenia. OBJECTIVE To evaluate associations of rs1344706 with brain structure and the core symptoms of schizophrenia. DESIGN Case-control analysis of covariance. SETTING University-based research...

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Identifiers

PMID: 22945618
DOI: 10.1001/archgenpsychiatry.2011.2116
PMCID: PMC3852666

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Influence of ZNF804a on brain structure volumes and symptom severity in individuals with schizophrenia.PMID 22945618Read ↗

A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes.Semantic proximity Read ↗

ZNF804A genetic variation (rs1344706) affects brain grey but not white matter in schizophrenia and healthy subjects.Semantic proximity Read ↗

ZNF804A rs1344706 is associated with cortical thickness, surface area, and cortical volume of the unmedicated first episode schizophrenia and healthy controls.Semantic proximity Read ↗

Association of the ZNF804A gene polymorphism rs1344706 with white matter density changes in Chinese schizophrenia.Semantic proximity Read ↗

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ZNF804A rs1344706 interacts with COMT rs4680 to affect prefrontal volume in healthy adults.Semantic proximity Read ↗

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