Article
ZNF804A risk allele is associated with relatively intact gray matter volume in patients with schizophrenia.
NeuroImage - 1 Feb 2011
Donohoe Gary, Rose Emma, Frodl Thomas, Morris Derek, Spoletini Ilaria, Adriano Fulvia, Bernardini Sergio, Caltagirone Carlo, Bossù Paola, Gill Michael, Corvin Aiden P, Spalletta Gianfranco
Abstract excerpt
ZNF804A rs1344706 is the first genetic risk variant to achieve genome wide significance for psychosis. Following earlier evidence that patients carrying the ZNF804A risk allele had relatively spared memory function compared to patient non-carriers, we investigated whether ZNF804A was also associated with variation in brain volume. In a sample of 70 patients and 38 healthy participants we used voxel based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.