Association of the ZNF804A gene polymorphism rs1344706 with white matter density changes in Chinese schizophrenia.

doi:10.1016/j.pnpbp.2011.08.021

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Article

Association of the ZNF804A gene polymorphism rs1344706 with white matter density changes in Chinese schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2012

Wei Qinling, Kang Zhuang, Diao Feici, Shan Baoci, Li Leijun, Zheng Liangrong, Guo Xiaofeng, Liu Chunlei, Zhang Jinbei, Zhao Jingping

Abstract excerpt

BACKGROUND: ZNF804A gene polymorphism rs1344706, the first genetic risk variant to achieve genome wide significance for schizophrenia, has been linked to neural functional connectivity. Dysconnectivity of WM may be the primary pathological mechanism of schizophrenia. Association of this variant with regional WM density has not been investigated in schizophrenic patients. METHODS: 69 healthy controls and 80...

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PMID: 21911029
DOI: 10.1016/j.pnpbp.2011.08.021

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