Article
TGF-β polymorphism and its expression correlated with CXCR4 expression in human breast cancer.
Molecular biology reports - 1 Dec 2012
Oda Julie Massayo Maeda, de Oliveira Karen Brajão, Guembarovski Roberta Losi, de Lima Kalil William Alves, da Silva do Amaral Herrera Ana Cristina, Guembarovski Alda Losi, Sobrinho Walter Jorge, Derossi Daniela Rudgeri, Watanabe Maria Angelica Ehara
Abstract excerpt
The role of chemokines and the growth factors has been extensively analyzed both in cancer risk and tumor progression. The transforming growth factor beta (TGF-β) and chemokine (C-X-C motif) receptor 4 (CXCR4) genes are implicated in several diseases, including breast cancer. Genomic DNA was obtained from 21 samples of peripheral blood or from normal tissue, previously fixed in formalin and embedded in paraffin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
