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Characterization of the Arginine Decarboxylase Gene (<scp>ORF HP</scp>0422, <i>speA</i>) Involved in Acid Tolerance in <i><scp>H</scp>elicobacter pylori</i>

17 Mar 2014

Abstract excerpt

BACKGROUND: Helicobacter pylori is a motile microaerophilic bacterium that colonizes the human stomach. H. pylori infection triggers gastric diseases, such as gastritis, peptic ulcer and gastric cancer. Stomach represents a barrier for microorganism colonization, particularly because of its high hydrochloric acid concentration. The main mechanism developed by H. pylori to maintain intracellular pH homeostasis in...

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PMID: 24628778
DOI: 10.1111/hel.12115

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