Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood-brain barrier model.

Brain research - 15 Oct 2012

Cantrill Carina A, Skinner Robert A, Rothwell Nancy J, Penny Jeffrey I

Abstract excerpt

Whilst it is well documented that all components of the neurovascular unit contribute to the restrictive nature of the blood-brain barrier (BBB), astrocytes have been identified as the cellular component most likely to play an essential role in maintaining the barrier properties. The aim of this study was to examine the impact of the rat astrocyte cell line, CTX-TNA2, on the structural and functional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Blood-Brain Barrier
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Endothelial Cells

Share to Models, Neurological

Share to Tight Junctions

Source

Identifiers

PMID: 22940232
DOI: 10.1016/j.brainres.2012.08.031

Genes

ABCB1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood-brain barrier model.PMID 22940232Read ↗

The Blood-Brain Barrier, an Evolving Concept Based on Technological Advances and Cell-Cell Communications.Semantic proximity Read ↗

Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrierSemantic proximity Read ↗

A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactionsSemantic proximity Read ↗

Modelling the Neurovascular Unit and the Blood-Brain Barrier with the Unique Function of PericytesSemantic proximity Read ↗

Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and AstrocytesSemantic proximity Read ↗

A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testingSemantic proximity Read ↗

An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.Semantic proximity Read ↗

Astrocytic contributions to blood-brain barrier (BBB) formation by endothelial cells: a possible use of aortic endothelial cell for in vitro BBB model.Semantic proximity Read ↗

Identification of neuronal and angiogenic growth factors in an in vitro blood-brain barrier model system: Relevance in barrier integrity and tight junction formation and complexity.Semantic proximity Read ↗

Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell modelsSemantic proximity Read ↗

Afamin is synthesized by cerebrovascular endothelial cells and mediates α‐tocopherol transport across an <i>in vitro</i> model of the blood–brain barrierSemantic proximity Read ↗

Engraftment of C6-2B cells into the striatum of ACI nude rats as a tool for comparison of the in vitro and in vivo phenotype of a glioma cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.