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Article

RAD51 135G>C polymorphism in esophageal cancer and meta-analysis in gastrointestinal tract cancers.

Journal of cancer research and therapeutics - 1 Dec 2022

Bali Jagmohan Singh, Sambyal Vasudha, Guleria Kamlesh, Mehrotra Sanjana, Singh Neeti Rajan, Uppal Manjit Singh, Manjari Mridu, Sudan Meena

Abstract excerpt

Background: A functional single-nucleotide polymorphism (SNP), 135G>C in the 5'UTR of the RAD51 gene, affects gene transcription activity with implications for the repair of damaged DNA related to tumorigenesis. Previous limited reported genetic studies to link the 135G>C polymorphism of RAD51 gene to the risk of gastrointestinal tract (GIT) cancers, especially esophageal cancer (EC), have been inconclusive....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36510976
DOI: 10.4103/jcrt.JCRT_784_20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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