Article
Paediatric-onset psoriasis is associated with ERAP1 and IL23R loci, LCE3C_LCE3B deletion and HLA-C*06.
The British journal of dermatology - 1 Oct 2012
Bergboer J G M, Oostveen A M, de Jager M E A, den Heijer M, Joosten I, van de Kerkhof P C M, Zeeuwen P L J M, de Jong E M G J, Schalkwijk J, Seyger M M B
Abstract excerpt
BACKGROUND: Recent genome-wide association studies have identified several genetic risk factors for psoriasis, but data on their association with age at onset are lacking. OBJECTIVES: To compare the association between known risk alleles and psoriasis in well-defined cohorts with paediatric- and adult-onset psoriasis. METHODS: Based on previous studies we selected seven genes and loci associated with psoriasis....
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