Article
[Correlation analysis of thrombin-activatable fibrinolysis inhibitor single nucleotide polymorphism with venous thromboembolism].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2012
Li Can, Hou Li-Hong, Liu Xiu-E, Huang Can, Wei Xiao-Hua
Abstract excerpt
This study was aimed to explore the change of single nucleotide polymorphism (SNP) of thrombin-activatable fibrinolysis inhibitor (TAFI) and its correlation of 2 sites (505a/g, 1040c/t) in its gene-coding region with venous thromboembolism (VTE). The genotype distribution of TAFI in 80 patients with VTE and 80 normal controls was detected by allele-specific PCR. The results showed that the distribution of each...
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