Article
GTP-binding-defective ARL4D alters mitochondrial morphology and membrane potential.
PloS one - 1 Jan 2012
Li Chun-Chun, Wu Tsung-Sheng, Huang Chun-Fang, Jang Li-Ting, Liu Yu-Tsan, You Shu-Ting, Liou Gunn-Guang, Lee Fang-Jen S
Abstract excerpt
ARL4D, ARL4A, and ARL4C are closely related members of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of GTPases. All three ARL4 proteins contain nuclear localization signals (NLSs) at their C-termini and are primarily found at the plasma membrane, but they are also present in the nucleus and cytoplasm. ARF function and localization depends on their controlled binding and hydrolysis of GTP. Here we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.