Article
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection.
PloS one - 1 Jan 2012
Woodham Andrew W, Da Silva Diane M, Skeate Joseph G, Raff Adam B, Ambroso Mark R, Brand Heike E, Isas J Mario, Langen Ralf, Kast W Martin
Abstract excerpt
Mucosotropic, high-risk human papillomaviruses (HPV) are sexually transmitted viruses that are causally associated with the development of cervical cancer. The most common high-risk genotype, HPV16, is an obligatory intracellular virus that must gain entry into host epithelial cells and deliver its double stranded DNA to the nucleus. HPV capsid proteins play a vital role in these steps. Despite the critical...
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