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Article

Mechanisms of cell entry by human papillomaviruses: an overview

20 Jan 2010

Abstract excerpt

As the primary etiological agents of cervical cancer, human papillomaviruses (HPVs) must deliver their genetic material into the nucleus of the target cell. The viral capsid has evolved to fulfil various roles that are critical to establish viral infection. The particle interacts with the cell surface via interaction of the major capsid protein, L1, with heparan sulfate proteoglycans. Moreover, accumulating...

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PMID: 20089191
DOI: 10.1186/1743-422x-7-11

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