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Article

Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.

American journal of physiology. Heart and circulatory physiology - 15 Oct 2012

Yamak Abir, Temsah Rana, Maharsy Wael, Caron Sophie, Paradis Pierre, Aries Anne, Nemer Mona

Abstract excerpt

Transcription factor GATA4 is a key regulator of cardiomyocyte growth, and differentiation and 50% reduction in GATA4 levels results in hypoplastic hearts. Search for GATA4 targets/effectors revealed cyclin D(2) (CD2), a member of the D-type cyclins (D(1), D(2), and D(3)) that play a vital role i...

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Source

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Identifiers

PMID: 22923619
DOI: 10.1152/ajpheart.00250.2012
PMCID: PMC3469642

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22923619-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.PMID 22923619Read ↗

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