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Article

Soluble ST2 protein inhibits LPS stimulation on monocyte-derived dendritic cells.

Cellular & molecular immunology - 1 Sept 2012

Nagata Akihisa, Takezako Naoki, Tamemoto Hiroyuki, Ohto-Ozaki Hiromi, Ohta Satoshi, Tominaga Shin-Ichi, Yanagisawa Ken

Abstract excerpt

ST2 protein is a soluble splicing variant of ST2L protein, which is the receptor for interleukin-33 (IL-33). Previously, we reported that soluble ST2 suppressed the signal transduction of lipopolysaccharide (LPS) and cytokine production in monocytic cells. To investigate whether or not this inhibitory effect occurs in dendritic cells, which are the key players in innate and adaptive immunity, human...

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Identifiers

PMID: 22922442
DOI: 10.1038/cmi.2012.29
PMCID: PMC4002335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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