Article
[Li-Fraumeni syndrome - a proposal of complex prevention care for carriers of TP53 mutation with total-body MRI].
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2012
Foretová L, Stěrba J, Opletal P, Mach V, Lisý J, Petráková K, Palácová M, Navrátilová M, Gaillyová R, Puchmajerová A, Křepelová A, Macháčková E
Abstract excerpt
Li-Fraumeni syndrome (LFS) is one of the most serious hereditary cancer syndromes with high risk of malignancy already in childhood. Adrenocortical carcinoma, brain tumor, leukemia, sarcoma are the most frequent malignancies in children. Early breast cancer, brain tumor, sarcoma, skin cancer, gastrointestinal, lung, gynecological, hematological and other malignancies can be seen in adults. Predictive testing in...
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