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Article

Characterization of bovine FUT7 furthers understanding of FUT7 evolution in mammals.

BMC genetics - 21 Aug 2012

Laporte Benoît, Petit Daniel, Rocha Dominique, Boussaha Mekki, Grohs Cécile, Maftah Abderrahman, Petit Jean-Michel

Abstract excerpt

BACKGROUND: The Sialyl-Lewis X (Slex) is a well-known glycan structure involved in leukocyte homing and recruitment to inflammatory sites. SLex is well conserved among species and is mainly synthesized by FucT-VII in vertebrates. The enzyme responsible for its biosynthesis in cattle was not known. RESULTS: We cloned a cDNA sequence encoding bovine α3-fucosyltransferase VII that shares 83% identity with its human...

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Identifiers

PMID: 22909383
DOI: 10.1186/1471-2156-13-74
PMCID: PMC3479001

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FUT7

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Characterization of bovine FUT7 furthers understanding of FUT7 evolution in mammals.PMID 22909383Read ↗

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