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Transcriptome analysis of a Pseudomonas aeruginosasn-glycerol-3-phosphate dehydrogenase mutant reveals a disruption in bioenergetics.

Microbiology (Reading, England) - 1 Apr 2018

Shuman Jon, Giles Tyler Xavier, Carroll Leslie, Tabata Kenji, Powers Austin, Suh Sang-Jin, Silo-Suh Laura

Abstract excerpt

Pseudomonas aeruginosa causes acute and chronic human infections and is the major cause of morbidity and mortality in cystic fibrosis (CF) patients. We previously determined that the sn-glycerol-3-phosphate dehydrogenase encoded by glpD plays a larger role in P. aeruginosa physiology beyond its role in glycerol metabolism. To better understand the effect of a glpD mutation on P. aeruginosa physiology we compared...

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Source

Identifiers

PMID: 29533746
DOI: 10.1099/mic.0.000646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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