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Article

Evidence of widespread selection on standing variation in Europe at height-associated SNPs.

Nature genetics - 1 Sept 2012

Turchin Michael C, Chiang Charleston W K, Palmer Cameron D, Sankararaman Sriram, Reich David, Hirschhorn Joel N

Abstract excerpt

Strong signatures of positive selection at newly arising genetic variants are well documented in humans(1-8), but this form of selection may not be widespread in recent human evolution(9). Because many human traits are highly polygenic and partly determined by common, ancient genetic variation, an alternative model for rapid genetic adaptation has been proposed: weak selection acting on many pre-existing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22902787
DOI: 10.1038/ng.2368
PMCID: PMC3480734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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