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Article

Association between polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and colorectal cancer risk.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Osawa Kayo, Nakarai Chiaki, Akiyama Minami, Hashimoto Ryuta, Tsutou Akimitsu, Takahashi Juro, Takaoka Yuko, Kawamura Shiro, Shimada Etsuji, Tanaka Kenichi, Kozuka Masaya, Yamamoto Masahiro, Kido Yoshiaki

Abstract excerpt

Genetic polymorphisms of uridine diphosphate-glucuronosyltransferases 1A6 (UGT1A6) and 1A7 (UGT1A7) may lead to genetic instability and colorectal cancer carcinogenesis. Our objective was to measure the interaction between polymorphisms of these repair genes and tobacco smoking in colorectal cancer (CRC). A total of 68 individuals with CRC and 112 non-cancer controls were divided into non-smoker and smoker groups...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22901212
DOI: 10.7314/apjcp.2012.13.5.2311

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