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Article

Interactions between MTHFR C677T-A1298C variants and folic acid deficiency affect breast cancer risk in a Chinese population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Wu Xia-Yu, Ni Juan, Xu Wei-Jiang, Zhou Tao, Wang Xu

Abstract excerpt

BACKGROUND: Our objective was to evaluate the MTHFR C677T-A1298C polymorphisms in patients with breast cancer and in individuals with no history of cancer, to compare the levels of genetic damage and apoptosis under folic acid (FA) deficiency between patients and controls, and to assess associations with breast cancer. METHODS: Genetic damage was marked by micronucleated binucleated cells (MNBN) and apoptosis was...

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Source

Identifiers

PMID: 22901194
DOI: 10.7314/apjcp.2012.13.5.2199

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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