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The myelin-deficient rat mutant: partial recovery of oligodendrocyte maturation in vitro.

Developmental neuroscience - 1 Jan 1990

Espinosa de los Monteros A, Zhang M, Gordon M N, Kumar S, Scully S A, de Vellis J

Abstract excerpt

The morphological and immunocytochemical identification and characterization of the myelin-forming cell, the oligodendrocyte, have defined a model system for developmental studies. The myelin-deficient (md) rat mutant lacks myelin in the central nervous system and fails to express the normal developmental increase in oligodendroglial and myelin markers, apparently as a consequence of a point mutation in the...

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Identifiers

PMID: 2289414
DOI: 10.1159/000111861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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