Article
Haplotype Analysis of Vitamin D Receptor (VDR) Gene in Breast Cancer Patients.
Clinical laboratory - 1 Jun 2021
Ergul Emel, Simsek Turgay, Uren Nihal, Korak Tugcan, Simsek Hayal U, Cine Naci, Canturk N Zafer, Utkan N Zafer
Abstract excerpt
BACKGROUND: The aim of the study was to evaluate the role of well-characterized vitamin D receptor (VDR) gene polymorphisms, BsmI (rs 1544410), ApaI (rs 7975232), TaqI (rs 731236), and FokI (rs 10735810) and their haplotypes in the pathogenesis of breast cancer in Turkish women. METHODS: The subjects consisted of women including 331 breast cancer patients and 345 healthy controls. After conventional DNA isolation...
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