Article
Netrins guide migration of distinct glial cells in the Drosophila embryo.
Development (Cambridge, England) - 1 Apr 2010
von Hilchen Christian M, Hein Irina, Technau Gerhard M, Altenhein Benjamin
Abstract excerpt
Development of the nervous system and establishment of complex neuronal networks require the concerted activity of different signalling events and guidance cues, which include Netrins and their receptors. In Drosophila, two Netrins are expressed during embryogenesis by cells of the ventral midline and serve as attractant or repellent cues for navigating axons. We asked whether glial cells, which are also motile,...
Topics
- Animals
- Cell Movement
- Cell Polarity
- Cues
- Drosophila
- Exons
- Immunohistochemistry
- Mutation
- Nerve Growth Factors
- Netrin-1
- Neuroglia
- Phenotype
- Signal Transduction
- Tumor Suppressor Proteins