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Article

A functional copy-number variation in MAPKAPK2 predicts risk and prognosis of lung cancer.

American journal of human genetics - 10 Aug 2012

Liu Bin, Yang Lei, Huang Binfang, Cheng Mei, Wang Hui, Li Yinyan, Huang Dongsheng, Zheng Jian, Li Qingchu, Zhang Xin, Ji Weidong, Zhou Yifeng, Lu Jiachun

Abstract excerpt

Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2) may promote cancer development and progression by inducing tumorigenesis and drug resistance. To assess whether the copy-number variation g.CNV-30450 located in the MAPKAPK2 promoter has any effect on lung cancer risk or progn...

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Identifiers

PMID: 22883146
DOI: 10.1016/j.ajhg.2012.07.003
PMCID: PMC3415537

Genes

MAPKAPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22883146-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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