Article
Highly pigmented <scp>T</scp>g(<scp><i>Grm1</i></scp>) mouse melanoma develops non‐pigmented melanoma cells in distant metastases
25 Jun 2012
Abstract excerpt
Murine model systems are critically required tools for the investigation of unknown mechanisms of melanoma development and metastasis and for developing more efficient therapies. The Tg(Grm1)EPv melanoma mouse model is characterized by spontaneous development of pigmented cutaneous melanomas at hairless skin regions, with a short latency and 100% penetrance. Local metastasis was described in initial analyses;...
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