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Article

FOXE1 polymorphisms are associated with familial and sporadic nonmedullary thyroid cancer susceptibility.

Clinical endocrinology - 1 Dec 2012

Tomaz Rute A, Sousa Inês, Silva Joana G, Santos Catarina, Teixeira Manuel R, Leite Valeriano, Cavaco Branca M

Abstract excerpt

OBJECTIVE: FOXE1 is a transcription factor required for thyroid differentiation and function. FOXE1 locus polymorphisms (chromosome 9q22.33) were recently associated with increased sporadic thyroid cancer risk. In this study, we aimed to investigate the association of FOXE1 variants with nonmedullary thyroid cancer (NMTC), in both sporadic and familial (FNMTC) cases from the Portuguese population. DESIGN AND...

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Source

Identifiers

PMID: 22882326
DOI: 10.1111/j.1365-2265.2012.04505.x

Genes

FOXE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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