Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using cases to strengthen inference on the association between single nucleotide polymorphisms and a secondary phenotype in genome-wide association studies.

Genetic epidemiology - 1 Jul 2010

Li Huilin, Gail Mitchell H, Berndt Sonja, Chatterjee Nilanjan

Abstract excerpt

Case-control genome-wide association studies provide a vast amount of genetic information that may be used to investigate secondary phenotypes. We study the situation in which the primary disease is rare and the secondary phenotype and genetic markers are dichotomous. An analysis of the associati...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Arylamine N-Acetyltransferase
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Models, Statistical

Share to Monte Carlo Method

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 20583284
DOI: 10.1002/gepi.20495
PMCID: PMC2918520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20583284-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using cases to strengthen inference on the association between single nucleotide polymorphisms and a secondary phenotype in genome-wide association studies.PMID 20583284Read ↗

Efficient adaptively weighted analysis of secondary phenotypes in case-control genome-wide association studies.Semantic proximity Read ↗

Proper analysis of secondary phenotype data in case-control association studies.Semantic proximity Read ↗

Robust analysis of secondary phenotypes in case-control genetic association studies.Semantic proximity Read ↗

Analysis of secondary phenotype involving the interactive effect of the secondary phenotype and genetic variants on the primary disease.Semantic proximity Read ↗

Estimation of odds ratios of genetic variants for the secondary phenotypes associated with primary diseases.Semantic proximity Read ↗

Adaptively weighted association statistics.Semantic proximity Read ↗

Testing Hardy-Weinberg proportions in a frequency-matched case-control genetic association study.Semantic proximity Read ↗

AWOT and CWOT for genotype and genotype-by-treatment interaction joint analysis in pharmacogenetics GWAS.Semantic proximity Read ↗

An optimal weighted aggregated association test for identification of rare variants involved in common diseases.Semantic proximity Read ↗

Genome-wide association scans for secondary traits using case-control samples.Semantic proximity Read ↗

Resampling-based multiple hypothesis testing procedures for genetic case-control association studies.Semantic proximity Read ↗

Power and type I error results for a bias-correction approach recently shown to provide accurate odds ratios of genetic variants for the secondary phenotypes associated with primary diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.