Article
New analysis of atypical spermatocytic tumours reveals extensive heterogeneity and plasticity of germ cell tumours†.
The Journal of pathology - 1 May 2024
Rajpert-De Meyts Ewa, Goriely Anne, Almstrup Kristian
Abstract excerpt
Testicular germ cell tumours (TGCTs) derived from immature (type I) and pluripotent germ cell neoplasia in situ (GCNIS, type II) are characterised by remarkable phenotypic heterogeneity and plasticity. In contrast, the rare spermatocytic tumour (SpT, type III), derived from mature spermatogonia, is considered a homogenous and benign tumour but may occasionally present as an anaplastic or an aggressive sarcomatoid...
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