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Article

Selection of resistance at lethal and non-lethal antibiotic concentrations.

Current opinion in microbiology - 1 Oct 2012

Hughes Diarmaid, Andersson Dan I

Abstract excerpt

Much of what we currently know about the genetics and evolution of antibiotic-resistance is based on selections with lethal drug concentrations that allow the detection of rare mutants with strong phenotypes. These data may be misleading with regard to the evolution of antibiotic resistance in natural environments, because bacteria are frequently exposed to concentration gradients of antibiotics. A significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22878455
DOI: 10.1016/j.mib.2012.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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