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Article

Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension.

Endocrinology - 1 Oct 2012

Penton David, Bandulik Sascha, Schweda Frank, Haubs Sophia, Tauber Philipp, Reichold Markus, Cong Lu Dang, El Wakil Abeer, Budde Thomas, Lesage Florian, Lalli Enzo, Zennaro Maria-Christina, Warth Richard, Barhanin Jacques

Abstract excerpt

Task1 and Task3 potassium channels (Task: tandem of P domains in a weak inward rectifying K(+) channel-related acid-sensitive K(+) channel) are believed to control the membrane voltage of aldosterone-producing adrenal glomerulosa cells. This study aimed at understanding the role of Task3 for the control of aldosterone secretion. The adrenal phenotype of Task3(-/-) mice was investigated using electrophysiology,...

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Identifiers

PMID: 22878402
DOI: 10.1210/en.2012-1527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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