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Article

Novel method for screening Saccharomyces cerevisiae mutants with increased sulfur-containing compounds: color-based selection of ade1 or ade2 mutants.

Journal of bioscience and bioengineering - 1 Dec 2012

Tarutina Marina G, Dutova Tatiana A, Yezhova Inna E, Nishiuchi Hiroaki, Sineoky Sergey P

Abstract excerpt

We identified Saccharomyces cerevisiae mutants with 100% higher intracellular glutathione using 1-methyl-3-nitro-1-nitrosoguanidine mutagenesis. This method employs visual selection of the most pigmented colonies among met30 strains carrying ade1 and ade2 mutations. Since the method does not involve genetic engineering, the mutants are suitable for use in the food industry.

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PMID: 22877685
DOI: 10.1016/j.jbiosc.2012.07.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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