Article
Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT.
Development (Cambridge, England) - 1 Jun 2014
Wong Michael D, Maezawa Yoshiro, Lerch Jason P, Henkelman R Mark
Abstract excerpt
The International Mouse Phenotyping Consortium (IMPC) plans to phenotype 20,000 single-gene knockout mice to gain an insight into gene function. Approximately 30% of these knockout mouse lines will be embryonic or perinatal lethal. The IMPC has selected three-dimensional (3D) imaging to phenotype these mouse lines at relevant stages of embryonic development in an attempt to discover the cause of lethality using...
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