Article
A bioimage informatics platform for high-throughput embryo phenotyping.
Briefings in bioinformatics - 1 Jan 2018
Brown James M, Horner Neil R, Lawson Thomas N, Fiegel Tanja, Greenaway Simon, Morgan Hugh, Ring Natalie, Santos Luis, Sneddon Duncan, Teboul Lydia, Vibert Jennifer, Yaikhom Gagarine, Westerberg Henrik, Mallon Ann-Marie
Abstract excerpt
High-throughput phenotyping is a cornerstone of numerous functional genomics projects. In recent years, imaging screens have become increasingly important in understanding gene-phenotype relationships in studies of cells, tissues and whole organisms. Three-dimensional (3D) imaging has risen to prominence in the field of developmental biology for its ability to capture whole embryo morphology and gene expression,...
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