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Article

A functional polymorphism in the interleukin-1beta and severity of nicotine dependence in male schizophrenia: a case-control study.

Journal of psychiatric research - 1 May 2015

Zhang Xiang Yang, Chen Da-Chun, Tan Yun-Long, Tan Shu-ping, Luo Xingguang, Zuo Lingjun, Rao Wenwang, Yu Qiong, Kou Changgui, Allen Melissa, Correll Christoph U, Wu Jingqin, Soares Jair C

Abstract excerpt

Previous studies have shown that the functional 511C/T polymorphism in the IL-1beta-gene may be implicated in the susceptibility for schizophrenia. Moreover, recent studies suggested that IL-1 participates in the progression of lung disease in smokers, which are overrepresented in schizophrenia. We aimed to investigate the possible relationship between the IL-1beta-511C/T polymorphism and smoking behavior in...

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PMID: 25858413
DOI: 10.1016/j.jpsychires.2015.03.015

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