Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?

Abstract excerpt

I discuss a very obscure activity of p53, namely suppression of senescence (gerosuppression), which is also manifested as anti-hypertrophic, anti-hypermetabolic, anti-inflammatory and anti-secretory effects of p53. But can gerossuppression suppress tumors?

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