Article
hMSH2 and hMLH1 gene expression patterns differ between lung adenocarcinoma and squamous cell carcinoma: correlation with patient survival and response to adjuvant chemotherapy treatment.
The International journal of biological markers - 27 Jan 2013
Vageli Dimitra P, Zaravinos Apostolos, Daniil Zoe, Dahabreh Jubrail, Doukas Sotirios G, Spandidos Demetrios A, Gourgoulianis Konstantinos I, Koukoulis George K
Abstract excerpt
BACKGROUND: We recently showed that the mRNA levels of mismatch repair (MMR) proteins in non-small cell lung carcinoma (NSCLC) tissue specimens and the phenotypic translation of molecular MMR data refines the biology of the MMR system with consequent diagnostic implications in the clinical assessment of lung cancer patients. METHODS: hMLH1 and hMSH2 mRNA expression was previously evaluated by qPCR for 29 NSCLC...
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