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Article

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation.

Leukemia - 1 Feb 2013

Lin X, Rice K L, Buzzai M, Hexner E, Costa F F, Kilpivaara O, Mullally A, Soares M B, Ebert B L, Levine R, Licht J D

Abstract excerpt

BCR-ABL-negative myeloproliferative neoplasms (MPNs) are most frequently characterized by the JAK2V617F gain-of-function mutation, but several studies showed that JAK2V617F may not be the initiating event in MPN development, and recent publications indicate that additional alterations such as chr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22864358
DOI: 10.1038/leu.2012.224

Genes

GBP2
JAK2
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22864358-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation.PMID 22864358Read ↗

Micro<scp>RNA</scp>s in myeloproliferative neoplasmsSemantic proximity Read ↗

Role of JAK2 V617F mutation and aberrant expression of microRNA-143 in myeloproliferative neoplasms.Semantic proximity Read ↗

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Mutations in the miR-142 gene are not common in myeloproliferative neoplasms.Semantic proximity Read ↗

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Mesenchymal stromal cells (MSC) from JAK2+ myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesisSemantic proximity Read ↗

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