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Article

FGFR1 is amplified during the progression of in situto invasive breast carcinoma

3 Aug 2012

Abstract excerpt

INTRODUCTION: Gene amplification is an important mechanism for activating oncogenes in malignant tumors. Although amplification of HER2, C-MYC, CCND1 and FGFR1 has been reported in breast cancers, their role in the progression of in situ to invasive breast carcinoma is unclear. To investigate this question we compared the amplification frequencies of these genes in pure ductal carcinoma in situ (DCIS), DCIS...

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PMID: 22863309
DOI: 10.1186/bcr3239

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