Article
Fibroblast-dependent regulation of the stem cell properties of cancer cells.
Neoplasma - 1 Jan 2012
Weiland A, Roswall P, Hatzihristidis T C, Pietras K, Ostman A, Strell C
Abstract excerpt
There is emerging evidence that cancer stem cells (CSCs), like normal tissue stem cells, are regulated by a niche formed of mesenchymal cells. In this review we summarize the current knowledge of the role of cancer associated fibroblasts (CAFs) in a tentative CSC niche. We also discuss findings f...
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