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Article

The role of 5-HTT LPR and GNβ3 825C>T polymorphisms and gene-environment interactions in irritable bowel syndrome (IBS).

Digestive diseases and sciences - 1 Oct 2012

Saito Yuri A, Larson Joseph J, Atkinson Elizabeth J, Ryu Euijung, Almazar Ann E, Petersen Gloria M, Talley Nicholas J

Abstract excerpt

BACKGROUND: Smaller studies have evaluated SLC6A4 5-HTTLPR and GNβ3 825C>T polymorphisms in IBS, and interactions between 5-HTT LPR with life events have been reported in the psychiatric literature, but gene-environment studies in IBS are lacking. AIMS: The purpose of this study was to assess the association of two polymorphisms with IBS and age of onset, and whether there are gene-environment interactions with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22855291
DOI: 10.1007/s10620-012-2319-9
PMCID: PMC3912694

Genes

HTT

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