Article
A genetic association study of 5-HTT LPR and GNbeta3 C825T polymorphisms with irritable bowel syndrome.
Neurogastroenterology and motility - 1 Jun 2007
Saito Y A, Locke G R, Zimmerman J M, Holtmann G, Slusser J P, de Andrade M, Petersen G M, Talley N J
Abstract excerpt
A pharmacogenetic study suggests the 5-HTT LPR polymorphism predicts response to alosetron, and another study describes a possible association of the GNbeta3 C825T polymorphism with IBS in patients with dyspepsia. We performed a case-control association study to determine whether these polymorphisms are associated with irritable bowel syndrome (IBS). The study aim was to compare allele and genotype frequencies...
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