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Article

Warfarin pharmacogenetics: development of a dosing algorithm for Omani patients.

Journal of human genetics - 1 Oct 2012

Pathare Anil, Al Khabori Murtadha, Alkindi Salam, Al Zadjali Shoaib, Misquith Rhea, Khan Hammad, Lapoumeroulie Claudine, Paldi Andras, Krishnamoorthy Rajagopal

Abstract excerpt

The objective of our present study was to develop a warfarin dosing algorithm for the Omani patients, as performances of warfarin dosing algorithms vary across populations with impact on the daily maintenance dose. We studied the functional polymorphisms of CYP2C9, CYP4F2 and VKORC1 genes to evaluate their impact on the warfarin maintenance dose in an admixed Omani patient cohort with Caucasian, African and Asian...

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Source

Identifiers

PMID: 22854539
DOI: 10.1038/jhg.2012.94

Genes

VKORC1

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Warfarin pharmacogenetics: development of a dosing algorithm for Omani patients.PMID 22854539Read ↗

Warfarin pharmacogenetics: polymorphisms of the CYP2C9, CYP4F2, and VKORC1 loci in a genetically admixed Omani population.Semantic proximity Read ↗

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