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Article

Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures

1 Aug 2012

Abstract excerpt

BACKGROUND: Aldehyde dehydrogenases belong to a superfamily of detoxifying enzymes that protect cells from carcinogenic aldehydes. Of the superfamily, ALDH1A1 has gained most attention because current studies have shown that its expression is associated with human cancer stem cells. However, ALDH1A1 is only one of the 19 human ALDH subfamilies currently known. The purpose of the present study was to determine if...

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PMID: 22852552
DOI: 10.1186/1471-2407-12-329

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