Article
Beyond differential expression: the quest for causal mutations and effector molecules.
BMC genomics - 31 Jul 2012
Hudson Nicholas J, Dalrymple Brian P, Reverter Antonio
Abstract excerpt
High throughput gene expression technologies are a popular choice for researchers seeking molecular or systems-level explanations of biological phenomena. Nevertheless, there has been a groundswell of opinion that these approaches have not lived up to the hype because the interpretation of the data has lagged behind its generation. In our view a major problem has been an over-reliance on isolated lists of...
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