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Article

The aromatase gene (CYP19A1) variants and circulating hepatocyte growth factor in postmenopausal women.

PloS one - 1 Jan 2012

Lin Jennifer H, Gunter Marc J, Manson JoAnn E, Rexrode Kathryn M, Cook Nancy R, Kraft Peter, Cochrane Barbara B, Chlebowski Rowan T, Ho Gloria Y F, Zhang Shumin M

Abstract excerpt

BACKGROUND: Estrogen and androgen have been linked to the regulation of circulating hepatocyte growth factor (HGF), an adipose tissue-derived cytokine. It is possible that the CYP19A1 gene which alters sex hormones production may influence HGF levels. We examined the association between the CYP19A1 gene variants and plasma HGF concentrations. DESIGN: We evaluated 45 common and putative functional variants of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22848710
DOI: 10.1371/journal.pone.0042079
PMCID: PMC3405042

Genes

HGF

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