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Article

Association of polymorphism in pri-microRNAs-371-372-373 with the occurrence of hepatocellular carcinoma in hepatitis B virus infected patients.

PloS one - 1 Jan 2012

Kwak Min-Sun, Lee Dong Hyeon, Cho Yuri, Cho Eun-Ju, Lee Jeong-Hoon, Yu Su Jong, Yoon Jung-Hwan, Lee Hyo-Suk, Kim Chung Yong, Cheong Jae Youn, Cho Sung Won, Shin Hyoung Doo, Kim Yoon Jun

Abstract excerpt

BACKGROUND: Micro RNAs-371-372-373 (miRNAs-371-373), originating from the same pri-miRNA transcript, are reported to be upregulated in hepatocellular carcinoma (HCC) and to be related to the regulation of hepatitis B virus (HBV) infection. Our study investigated whether pri-miRNAs-371-373 polymorphisms are associated with the risk of HCC occurrence and HBV clearance. METHODS: Genetic variations were identified...

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Identifiers

PMID: 22848681
DOI: 10.1371/journal.pone.0041983
PMCID: PMC3407047

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Source receipt: pubmed, retrieved 7 Sept 2026.

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