Article
Association of polymorphism in pri-microRNAs-371-372-373 with the occurrence of hepatocellular carcinoma in hepatitis B virus infected patients.
PloS one - 1 Jan 2012
Kwak Min-Sun, Lee Dong Hyeon, Cho Yuri, Cho Eun-Ju, Lee Jeong-Hoon, Yu Su Jong, Yoon Jung-Hwan, Lee Hyo-Suk, Kim Chung Yong, Cheong Jae Youn, Cho Sung Won, Shin Hyoung Doo, Kim Yoon Jun
Abstract excerpt
BACKGROUND: Micro RNAs-371-372-373 (miRNAs-371-373), originating from the same pri-miRNA transcript, are reported to be upregulated in hepatocellular carcinoma (HCC) and to be related to the regulation of hepatitis B virus (HBV) infection. Our study investigated whether pri-miRNAs-371-373 polymor...
Topics
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Male
- MicroRNAs
- Middle Aged
